Draft Class 1981
0 picks on file, plus 6 who entered the league undrafted.
| Pick | Player | Drafted by | School | Career |
|---|---|---|---|---|
| UDFA | David Cone P | — | — | Batting .200 AVG · 0 HR · 0 RBI |
| UDFA | John Franco P | — | — | Batting 0 HR · 0 RBI |
| UDFA | Tony Gwynn RF | — | — | — |
| UDFA | Fred McGriff 1B | — | — | Batting .258 AVG · 45 HR · 150 RBI |
| UDFA | Paul O'Neill RF | — | — | — |
| UDFA | Devon White CF | — | — | — |