| # | Player | Team | W | L | SV | G | GS | QS | IP | IP/G | SO ▾ | K/9 | BB/9 | ERA | FIP | WAR |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Jacob Misiorowski | MIL | 12 | 5 | 0 | 23 | 23 | 14 | 139.0 | 6.0 | 210 | 13.6 | 2.0 | 1.75 | 2.16 | 5.1 |
| 2 | Dylan Cease | TOR | 7 | 5 | 0 | 23 | 23 | 11 | 137.2 | 6.0 | 201 | 13.1 | 3.9 | 2.42 | 2.41 | 4.5 |
| 3 | Gavin Williams | CLE | 11 | 7 | 0 | 25 | 25 | 9 | 149.0 | 6.0 | 190 | 11.5 | 2.7 | 3.74 | 3.41 | 2.9 |
| 4 | Cam Schlittler | NYY | 10 | 6 | 0 | 26 | 26 | 15 | 152.0 | 5.8 | 189 | 11.2 | 2.0 | 2.19 | 2.60 | 4.7 |
| 5 | Jesús Luzardo | PHI | 11 | 5 | 0 | 25 | 25 | 13 | 150.1 | 6.0 | 185 | 11.1 | 2.8 | 3.23 | 2.82 | 4.3 |
| 6 | Cristopher Sánchez | PHI | 15 | 4 | 0 | 25 | 25 | 17 | 155.2 | 6.2 | 181 | 10.5 | 2.0 | 2.54 | 2.61 | 5.0 |
| 7 | Reid Detmers | LAA | 4 | 8 | 0 | 25 | 25 | 9 | 143.0 | 5.7 | 167 | 10.5 | 2.7 | 3.78 | 3.45 | 3.0 |
| 8 | Paul Skenes | PIT | 9 | 11 | 0 | 25 | 25 | 10 | 134.2 | 5.4 | 166 | 11.1 | 2.5 | 3.88 | 2.99 | 3.7 |
| 9 | Chris Sale | ATL | 12 | 8 | 0 | 22 | 22 | 14 | 129.0 | 5.9 | 160 | 11.2 | 2.0 | 2.16 | 2.40 | 4.2 |
| 10 | Nolan McLean | NYM | 8 | 8 | 0 | 24 | 24 | 14 | 136.2 | 5.7 | 159 | 10.5 | 3.3 | 3.42 | 3.56 | 2.6 |
| 11 | Braxton Ashcraft | PIT | 12 | 5 | 0 | 24 | 24 | 11 | 141.1 | 5.9 | 155 | 9.9 | 2.1 | 3.88 | 3.58 | 2.9 |
| 12 | Sean Burke | CWS | 7 | 6 | 0 | 25 | 21 | 10 | 140.0 | 5.6 | 154 | 9.9 | 2.7 | 3.15 | 3.32 | 3.1 |
| 13 | MacKenzie Gore | TEX | 7 | 9 | 0 | 26 | 26 | 8 | 139.2 | 5.4 | 154 | 9.9 | 3.3 | 4.45 | 3.74 | 2.4 |
| 14 | Logan Gilbert | SEA | 9 | 7 | 0 | 24 | 24 | 12 | 145.1 | 6.1 | 152 | 9.4 | 2.0 | 3.28 | 3.47 | 2.8 |
| 15 | Chase Burns | CIN | 14 | 2 | 0 | 23 | 23 | 10 | 131.0 | 5.7 | 151 | 10.4 | 3.2 | 2.47 | 3.27 | 3.5 |
| 16 | Taj Bradley | MIN | 9 | 5 | 0 | 24 | 24 | 11 | 135.2 | 5.7 | 151 | 10.0 | 3.9 | 3.98 | 4.05 | 1.8 |
| 17 | Cade Cavalli | WSH | 10 | 5 | 0 | 26 | 26 | 14 | 136.2 | 5.3 | 151 | 9.9 | 2.7 | 3.36 | 3.46 | 2.7 |
| 18 | Jacob deGrom | TEX | 8 | 8 | 0 | 23 | 23 | 8 | 120.2 | 5.2 | 147 | 11.0 | 2.3 | 3.95 | 3.25 | 3.0 |
| 19 | Parker Messick | CLE | 9 | 7 | 0 | 24 | 24 | 9 | 142.1 | 5.9 | 142 | 9.0 | 2.5 | 2.59 | 3.25 | 3.5 |
| 20 | Ryan Weathers | NYY | 5 | 7 | 0 | 24 | 24 | 8 | 134.0 | 5.6 | 140 | 9.4 | 2.6 | 3.56 | 3.73 | 2.2 |
| 21 | Joey Cantillo | CLE | 9 | 7 | 0 | 26 | 26 | 4 | 125.2 | 4.8 | 139 | 10.0 | 4.2 | 3.80 | 3.96 | 1.7 |
| 22 | Joe Ryan | MIN | 6 | 8 | 0 | 23 | 23 | 11 | 125.2 | 5.5 | 138 | 9.9 | 1.9 | 3.65 | 3.41 | 2.7 |
| 23 | Aaron Nola | PHI | 4 | 9 | 0 | 25 | 25 | 7 | 130.0 | 5.2 | 138 | 9.6 | 3.2 | 5.33 | 5.04 | 0.7 |
| 24 | Kevin Gausman | CHC | 6 | 11 | 0 | 25 | 25 | 12 | 139.0 | 5.6 | 138 | 8.9 | 2.5 | 4.53 | 3.53 | 2.8 |
| 25 | Zack Wheeler | PHI | 10 | 4 | 0 | 20 | 20 | 12 | 115.1 | 5.8 | 137 | 10.7 | 2.3 | 2.89 | 3.12 | 3.1 |
| 26 | Nathan Eovaldi | TEX | 10 | 9 | 0 | 22 | 22 | 11 | 132.2 | 6.0 | 137 | 9.3 | 2.2 | 4.21 | 4.25 | 1.6 |
| 27 | Bryan Woo | SEA | 9 | 8 | 0 | 24 | 24 | 12 | 138.1 | 5.8 | 137 | 8.9 | 1.9 | 4.10 | 3.13 | 3.2 |
| 28 | Yoshinobu Yamamoto | LAD | 12 | 7 | 0 | 22 | 22 | 16 | 145.1 | 6.6 | 136 | 8.4 | 2.1 | 2.60 | 3.43 | 3.3 |
| 29 | Tarik Skubal | LAD | 7 | 7 | 0 | 19 | 19 | 10 | 113.2 | 6.0 | 135 | 10.7 | 1.6 | 2.85 | 2.79 | 3.0 |
| 30 | José Soriano | TOR | 9 | 6 | 0 | 24 | 24 | 9 | 133.2 | 5.6 | 134 | 9.0 | 4.2 | 3.16 | 3.82 | 2.2 |
| 31 | Drew Rasmussen | TB | 12 | 5 | 0 | 23 | 23 | 13 | 129.1 | 5.6 | 133 | 9.3 | 1.6 | 2.78 | 2.93 | 3.7 |
| 32 | Eury Pérez | MIA | 6 | 9 | 0 | 22 | 22 | 10 | 122.2 | 5.6 | 133 | 9.8 | 3.6 | 3.23 | 3.67 | 2.3 |
| 33 | Sandy Alcantara | MIA | 13 | 7 | 0 | 26 | 26 | 18 | 170.2 | 6.6 | 130 | 6.9 | 2.4 | 3.43 | 3.76 | 3.0 |
| 34 | Shota Imanaga | CHC | 8 | 9 | 0 | 24 | 24 | 10 | 137.1 | 5.7 | 130 | 8.5 | 1.9 | 3.74 | 4.56 | 1.3 |
| 35 | Payton Tolle | BOS | 8 | 6 | 0 | 20 | 20 | 11 | 115.0 | 5.8 | 128 | 10.0 | 2.4 | 2.97 | 3.21 | 3.1 |
| 36 | Landen Roupp | SF | 7 | 12 | 0 | 24 | 24 | 10 | 129.1 | 5.4 | 128 | 8.9 | 4.2 | 4.31 | 3.52 | 2.3 |
| 37 | José Soriano | LAA | 9 | 6 | 0 | 22 | 22 | 8 | 123.0 | 5.6 | 127 | 9.3 | 4.2 | 3.29 | 3.79 | 2.1 |
| 38 | Kevin Gausman | TOR | 5 | 10 | 0 | 23 | 23 | 11 | 127.1 | 5.5 | 127 | 9.0 | 2.5 | 4.38 | 3.50 | 2.6 |
| 39 | Noah Cameron | KC | 7 | 8 | 0 | 24 | 23 | 7 | 138.1 | 5.8 | 126 | 8.2 | 2.8 | 4.16 | 3.71 | 2.2 |
| 40 | Foster Griffin | CLE | 13 | 4 | 0 | 24 | 24 | 12 | 138.1 | 5.8 | 125 | 8.1 | 2.1 | 3.25 | 4.23 | 1.7 |
| 41 | Michael King | SD | 8 | 8 | 0 | 25 | 25 | 11 | 142.1 | 5.7 | 124 | 7.8 | 3.5 | 3.41 | 4.16 | 2.0 |
| 42 | Kyle Bradish | BAL | 7 | 11 | 0 | 24 | 24 | 11 | 133.0 | 5.5 | 124 | 8.4 | 3.9 | 3.65 | 3.85 | 1.9 |
| 43 | Freddy Peralta | TB | 5 | 10 | 0 | 25 | 25 | 5 | 128.0 | 5.1 | 123 | 8.6 | 3.7 | 5.27 | 4.56 | 1.1 |
| 44 | Shane Baz | BAL | 4 | 12 | 0 | 24 | 24 | 10 | 139.1 | 5.8 | 122 | 7.9 | 3.0 | 4.00 | 3.34 | 3.0 |
| 45 | Max Meyer | MIA | 9 | 1 | 0 | 20 | 20 | 7 | 111.0 | 5.6 | 121 | 9.8 | 3.3 | 2.68 | 3.49 | 2.4 |
| 46 | Emerson Hancock | SEA | 7 | 7 | 0 | 23 | 23 | 11 | 128.0 | 5.6 | 119 | 8.4 | 2.3 | 3.30 | 3.73 | 1.8 |
| 47 | Sonny Gray | BOS | 15 | 3 | 0 | 23 | 23 | 15 | 132.2 | 5.8 | 117 | 7.9 | 2.3 | 2.65 | 3.58 | 2.3 |
| 48 | Peter Lambert | HOU | 8 | 6 | 0 | 21 | 21 | 8 | 118.2 | 5.7 | 117 | 8.9 | 3.5 | 3.11 | 3.87 | 1.9 |
| 49 | Michael Wacha | KC | 5 | 8 | 0 | 24 | 24 | 16 | 150.2 | 6.3 | 117 | 7.0 | 2.4 | 3.46 | 4.00 | 2.3 |
| 50 | Tanner Bibee | CLE | 4 | 13 | 0 | 26 | 26 | 14 | 150.1 | 5.8 | 117 | 7.0 | 2.6 | 4.01 | 4.51 | 1.2 |
868 players